SCD Today

What is Sickle Cell Disease

SCD is a genetic blood disorder caused by mutations in the hemoglobin gene, leading to abnormal, crescent-shaped red blood cells. People with sickle cell disorder are born with the condition, it is not contagious. It can only be inherited from both parents each having passed on the gene for sickle cell.

The main symptoms of sickle cell disorder are anaemia and episodes of severe pain. The pain occurs when the cells change shape after oxygen has been released. The red blood cells then stick together, causing blockages in the small blood vessels. SCD patients experience also organ damage, reduced lifespan, and impaired quality of life.

SIMPLE FACTS

Current Treatments for SCD

Limited Options for a Complex Disease

SCD treatments aim to manage symptoms, prevent complications, and improve quality of life. The most common treatment is hydroxyurea, a medication that helps increase fetal hemoglobin levels, reducing the frequency of painful crises and the need for blood transfusions. Pain management is also crucial. Blood transfusions may be used to treat anemia and prevent stroke in high-risk patients. Additionally, bone marrow or stem cell transplants can offer a potential cure but are limited to specific cases due to the need for a compatible donor.